High Precision, Non-invasive Skin Closures
- Advanced Wound Closures with Interlaced Locking Technology
- A simple and secure solution to close and heal surgical incisions and traumatic lacerations.
- Clozex provides Next Generation Wound Closure Technology.
Clinical Efficacy: Clozex advanced non-invasive wound closure has produced excellent results in more than 10,000 surgical procedures including multiple orthopedic applications – joint replacement, wound closure following fracture fixation, and pediatric spinal and limb surgery. Clozex also has demonstrated effectiveness in cardiothoracic surgical procedures, plastic surgery, and dermatological procedures as well as abdominal surgeries such as hernia repair and bariatric procedures.
Applying Clozex



Clinically proven to minimize unnecessary scarring.
See the results for yourself.





50mm Clozex on Skin


The efficacy of Clozex has been proven in Emergency Departments and Urgent Care centers as well as in surgical specialties.
Benefits
Fast and Durable Skin Closure
- Closes skin 2x faster with Clozex, compared to subcuticular suture(3).
- Provides cross-incisional strength with similar holding durability as sutures(10).
- Reduce OR costs and free up valuable personal and administrative time for surgeons and staff(5).
Easy to Learn and Apply
- Allows all providers the ability to easily close wounds with high precision and great clinical outcomes.
- Highly transferable and easily learned wound closure method for field-based employees covering multiple sites.
Patient-Friendly Technology
- Non-threatening during placement and removal – Great for children and elderly patients.
- Non-intrusive and easily removed by you or the patient, potentially eliminating the need for a follow-up visit.
- Clozex does not need to be removed by a certain time, unlike sutures which accentuate scarring if left in place for too long.
Greater Control and Flexibility
- Simultaneously align skin edges in all 3 dimensions (across, along, and perpendicular to the skin surface) with one simple pulling motion.
- Versatile closure can be overlapped to close angled or curved wounds, and a variety of anatomical structures.
- Close each segment of a long incision with precision, preventing waviness and buckling along the incision line.
Safer, Non-Invasive Design
- Reduce risk of surgical site infections caused when sutures pierce the skin and allow bacteria to colonize and wick into the wound.
- Create a safer environment for surgeons and OR staff, by adopting a needleless solution.
Excellent Cosmetic Results
- Non-invasive, topical skin closure device eliminates unnecessary “track marks” caused by sutures and staples(1,4).
- Reduces scar-producing tension by evenly distributing forces along the entire length of the wound edges(1,4).
- Interlaced technology aligns and securely maintains skin edges in the same planar level, promoting optimal healing.
Clozex is Available in Multiple Sizes


Clozex Documents (PDFs)
References
1. Anuar Ramdhan I, Zulmi W, Hidayah A, Kamel M, Fadhil M, Anwar Hau M. Comparative study between coaptive film versus suture for wound closure after long bone fracture fixation. Malays Orthop J. 2013 Mar;7(1):52-5.
2. Buttaravoli P, Leffler SM. Minor Emergencies (Third Edition), Elsevier 2012.
3. Grottkau BE, Rebello G, Merlin G, Winograd JM. Coaptive film versus subcuticular suture: comparing skin closure time after posterior spinal instrumented fusion in pediatric patients with spinal deformity. Spine (Phila Pa 1976). 2010 Nov 1;35(23):2027-9.
4. Lazar HL, McCann J, Fitzgerald CA, Thompson J, Bao Y, Cabral HJ. Novel adhesive skin closures improve wound healing following saphenous vein harvesting. J Card Surg. 2008 Mar-Apr;23(2):152-5.
5. Rebello G, Parikh R, Grottkau B. Coaptive film versus subcuticular suture: comparing skin closure time following identical, single-session, bilateral limb surgery in children. J Pediatr Orthop. 2009 Sep;29(6):626-8.
10. Kuo F, Lee D, Rogers GS. Prospective, randomized, blinded study of a new wound closure film versus cutaneous suture for surgical wound closure. Dermatol Surg. 2006 May;32(5):676-81.